Monday August 15, 2016
| Away | Home | Time (ET) |
| Red Sox | Indians | 1:10 PM |
| Blue Jays | Yankees | 7:05 PM |
| Royals | Tigers | 7:10 PM |
| Marlins | Reds | 7:10 PM |
| Padres | Rays | 7:10 PM |
| Athletics | Rangers | 8:05 PM |
| Nationals | Rockies | 8:40 PM |
| Mets | D-backs | 9:40 PM |
| Mariners | Angels | 10:05 PM |
| Pirates | Giants | 10:15 PM |
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